Trauma-informed care (TIC) has become a foundational approach in healthcare, aiming to address the profound effects of trauma on individuals’ well-being. This framework involves recognizing, understanding, and responding to the impact of trauma on patients’ mental, emotional, and physical health. Nurses play a critical role in applying TIC principles by creating safe, supportive environments, assessing trauma-related symptoms, and collaborating with patients to design personalized care plans. This approach also emphasizes the significance of including trauma histories in nursing assessments and treatment planning while addressing both immediate and long-term health impacts, including those related to adverse childhood experiences (ACEs).