Letter collections provide a vital source for our understanding of medical care in the late medieval home. In this domestic context, medical care was often provided by women, who had no formal medical education. Household books and conduct literature can inform us about the expectation that women would provide medical care for their family and social networks but not evidence of lived experience. Letters, such as those of the Armburgh, Paston, and Stonor families, show this lived experience. They show how women interacted in social networks of care, spreading medical recipes and theories with their family and friends. This contribution focuses primarily on the letter collections of the late medieval English gentry. Letters, such as those of the Armburgh, Paston, and Stonor families, provide an essential glimpse of domestic medical practice. They show how women interacted in social networks of care and shared medical recipes and theories with their family and friends highlighting the scope of their medical practice.