Therapeutic thoughts are thoughts that can help and heal when individuals face significant life stress events. They are grounded in the observation of hundreds of improved cases, from clinical and research studies on stress and coping, from clinical research studies on the mechanisms of change and healing in psychotherapy, and from informal exchanges of opinions of colleagues psychologists, and psychiatrists of different orientations. The mind performs many essential self-regulatory functions, maintaining a balance, for example, between thoughts that generate anxiety (anxiogenic and panicogenic) and those that lead to depression (depressogenic and rumination). This chapter presents several types of therapeutic thoughts such as anxiolytic and anti-panic thoughts, antidepressant thoughts, anti-obsessive and anti-psychotic thoughts, as well as existential thoughts related to life trajectories, gratitude, personal situations, learning to cope with life stressors; constructive reactions, recognizing a turning point in life, and personal transformation. They are presented and explored through a Socratic dialogue; allowing them to be learned and made their own by the patient in their self-talk.