The Department of Health and Human Services defines underserved communities as those populations who face barriers in accessing and using health-related services. These populations include communities of color (e.g., Black, Hispanic (government classification), American Indian/Alaskan Native) that have experienced institutional racism resulting in social and financial inequities creating those barriers. Lack of quality health services not related to access, cultural needs, preferences, or appropriateness of intervention results in health disparities (Smedley B, Stith A, Nelson A. Unequal treatment: confronting racial and ethnic disparities in health care. National Academies Press, 2003), the preventable differences in the burden of disease, injury, violence, or opportunities to achieve optimal health that are experienced by disadvantaged populations. In an ideal world, all persons would have the opportunity to attain his/her/their full health potential with no barrier to that potential due to social position or other societally determined factors, health equity (Smedley B, Stith A, Nelson A. Unequal treatment: confronting racial and ethnic disparities in health care. National Academies Press, 2003). Disparities in care exist at every level of the resource continuum creating challenges to the attainment of health equity. This goal is particularly challenging in underserved and under-resourced populations. This is a global dilemma that can be addressed with intentional actions.