This paper explores the ethical issues of Simulation and Gaming. Although there has been an extensive discussion on this topic, it has recently gained increasing relevance within a time of defying borders. Therefore, a reexamination of these topics from this new point of view becomes necessary. Firstly, the importance of this research is further elaborated on. When we refer to a border, we may imagine a country’s border. However, we have created many kinds of ‘borders’ around us, for instance the dividing lines we have drawn and continue to draw between different cultures or gender identities. The need for defying and crossing these self-imposed borders has become clearly evident in a world full of diversity. The issue of crossing and overcoming these boundaries can then be interpreted as to how sustainably and appropriately we deal with this diversity. Managing diversity, equity and inclusion thus becomes increasingly ethical issue also for the discipline of Gaming Simulation. In the paper, the presented ethical viewpoints are explored from three perspectives, namely the ones of game design, game facilitation and debriefing, and game content. Lastly, we conclude with some proposals for the Simulation and Gaming community based on our discussion.