Given the prevailing migration crisis in Latin America, governments and humanitarian organizations have implemented the technologization of border controls and shifting toward smart borders with the consequent use of biometric technologies and artificial intelligence for the control and processing of massive amounts of information. This chapter presents the context of the migration crisis on the continent, as well as the technologization of immigration procedures and the periodic implementation of biometric technologies, artificial intelligence, and massive data processing for the purpose of border security and control, specifically in the case of the border between the United States and Brazil. Secondly, the violation of migrants’ human rights is analyzed through the use of these technologies to collect personal and biometric data in the different contexts of the migration process in these countries, in contrast to the legislation and treaties of the United States and Brazil, as well as the humanitarian organizations involved. The work of civil movements in support of the protection of personal and biometric data and the human rights of migrants is also presented.