Stressful events can cause negative emotions in people, which, in turn, can have a negative impact on their mental as well as their physical health. With the help of different coping strategies, however, accompanying negative emotions can be reduced while positive emotions may be enhanced. Which coping strategy a person selects can depend on personal, situational, and contextual factors. Culture may play a vital role in such decision processes. This chapter provides an overview of theoretical models on coping and related empirical studies with an emphasis on cross-culturally comparative research. Existing studies can be classified in three research perspectives, namely absolutism, universalism, and relativism. At the beginning of this chapter, the different perspectives are introduced, followed by a description of the levels on which cultural comparisons may take place. The absolutist perspective of coping research has widely proven empirically untenable, leaving the universalist approach to dominate empirical research for years. Studies in the tradition of the relativist approach have gained more prominence in the recent past, with the present chapter summarizing prevalent coping strategies of selected cultural groups in more detail by way of example.