The rise of Information Technologies’ influence during the 3rd industrial revolution led to the development of Digital Health Records, with Electronic Health Records (EHRs) and Personal Health Records (PHRs) beginning patient empowerment. Today, Health Wallets (HWs), leveraging technologies like Fast Healthcare Interoperability Resources (FHIR) and Blockchain, represent the next step in this evolution, focusing on patient-centric health management, and the growing need for availability, transparency, privacy, and reliability. The paper, henceforth, will conduct a Systematic Literature Review, following the PRISMA framework, with the aim of exploring the characteristics of existing patient information platforms, the advantages and limitations of their use, and gaps in the current solutions. An initial search yielded 850 articles, of which 36 were included in the analysis. The results show that healthcare professionals generally support the integration of HWs into practice, with accelerated research and implementation following the COVID-19 pandemic. These platforms aim for secure data management, although challenges persist, particularly in terms of interoperability, and data protection. Benefits include Patient empowerment, better treatment, and cost reduction as well as operational efficiency. Despite some resistance due to established routines and patient eHealth literacy, key issues are mitigated by key technologies such as FHIR, Blockchain, Role Based Access Control (RBAC), and Bidirectional Communication. Research should focus on the ability of Health Wallets to integrate seamlessly with existing systems to avoid additional complexity, enhance privacy, enhance user experience, and improve healthcare efficiency.