Total arterial compliance (TAC) is a critical cardiovascular parameter that significantly influences central blood pressure and cardiac load. It plays a crucial role in evaluating cardiovascular disease risk and monitoring the progress of treatments. In this study, we employ a specialized blood pressure measurement technique that integrates a constant pressure procedure within the oscillometric method. This approach is followed by analyzing the blood pressure waveform using the Windkessel model. By observing the changes in the diastolic phase of the blood pressure curve, we conduct a cold pressor test to create conditions that alter vascular stiffness. This test involves immersing a participant’s hand or foot in ice water, which induces vasoconstriction and modifies arterial compliance. The study estimates arterial compliance parameters based on these observations. The results reveal that, following the cold pressor test, the arterial compliance parameter decreased by 34% compared to baseline, demonstrating a significant reduction and highlighting the impact of cold-induced changes in vascular stiffness on arterial compliance.

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The Performance of the Total Arterial Compliance Index via the Oscillometric Constant Pressure Method in the Cold Pressor Test

  • Shi-Yi Wu,
  • Shao-Hung Lu,
  • Liang-Yu Hsu,
  • Cheng-Lun Tsai,
  • Kang-Ping Lin

摘要

Total arterial compliance (TAC) is a critical cardiovascular parameter that significantly influences central blood pressure and cardiac load. It plays a crucial role in evaluating cardiovascular disease risk and monitoring the progress of treatments. In this study, we employ a specialized blood pressure measurement technique that integrates a constant pressure procedure within the oscillometric method. This approach is followed by analyzing the blood pressure waveform using the Windkessel model. By observing the changes in the diastolic phase of the blood pressure curve, we conduct a cold pressor test to create conditions that alter vascular stiffness. This test involves immersing a participant’s hand or foot in ice water, which induces vasoconstriction and modifies arterial compliance. The study estimates arterial compliance parameters based on these observations. The results reveal that, following the cold pressor test, the arterial compliance parameter decreased by 34% compared to baseline, demonstrating a significant reduction and highlighting the impact of cold-induced changes in vascular stiffness on arterial compliance.