The chapter, Science and Intelligence, looks at the underlying knowledge-related concepts relevant to climate security intelligence from an intelligence community and a scientific perspective. The chapter begins with the distinction between knowledge and judgment, briefly addresses the difference between artificial (synthetic) knowledge and human judgment, and discusses the contribution of artificial intelligence and scenario simulations to climate security impacts. Second, the chapter discusses structural differences in collaboration between the intelligence community and the scientific community by examining knowledge disciplines and types of knowledge integration. Third, it explains the cultural differences between the two communities and how it affects climate security intelligence understanding and interactions.