In this chapter I address a shift that has taken place in attitudes about nihilism over the past few decades. Whereas in previous times nihilism was most commonly treated as a wholly negative phenomenon, in recent times it has undergone a reassessment, with many philosophers, scholars, and the general public increasingly coming to consider it as unthreatening, and even beneficial. This shift makes it easier than ever to understand how humor rather than despair is a possible, appropriate, and desirable response to nihilism. I argue that nihilism is structured in terms of a particular kind of incongruity that I call “nihilistic incongruity.” Since nihilistic incongruity has come to be perceived as less of a threat than ever before, and since humor rests on the recognition of non-threatening incongruities, I conclude that it has today become easier and more appropriate than ever to adopt a humorous attitude toward nihilism.