The chapter addresses the gap in African-European and Intra-African intercultural communication studies by examining theoretical concepts and presenting empirical findings. This study draws on 17 interviews conducted with professionals and students who have first-hand experience in African-European and Intra-African intercultural cooperation. The research focuses on recurring themes such as cultural belonging, obstacles encountered, benefits derived, and strategies employed to enhance intercultural collaboration. The findings highlight certain cultural distinctions in how individuals approach interculturality and navigate challenges. However, the study emphasizes the predominance of universal principles in fostering successful intercultural experiences. Key elements include the use of a common language, a willingness to question assumptions, acknowledgment of cultural differences, and a focus on shared goals. The authors argue that intercultural competence training plays a critical role in achieving effective and harmonious cooperation.