Economic instability—whether prosperity or downturn—has profound implications for mental health, workplace stability, and suicide rates. This chapter explores three sociological theories that examine this connection: Durkheim’s dual-cycle hypothesis, which suggests suicide rates rise during both economic expansions and recessions; Ginsberg’s theory, which associates higher suicide rates with economic growth; and Henry and Short’s perspective, which attributes increased suicide rates to financial downturns. Empirical data largely support Durkheim’s theory, underscoring how sudden changes—rather than economic hardship alone—can lead to psychological distress and suicidal behaviors. Organizations cannot afford to overlook these findings. Economic pressures influence job security, stress levels, and workplace morale, making corporate responsibility in mental health support crucial. Businesses must act by cultivating emotionally intelligent leadership, applying behavioral economic strategies, and implementing proactive mental health programs. Supportive work cultures can buffer employees against economic-related anxiety, offering protection against the ripple effects of financial instability. By bridging sociological research with real-world organizational practices, this chapter provides strategies for institutions to safeguard employee well-being. Recognizing the link between economics and suicide is not just an academic exercise—it is an urgent call for businesses to lead with empathy, resilience, and forward-thinking policies that protect their workforce.