Knowledge of the incidence and distribution of inflammatory responses can help clinicians understand orbital disorders and establish standard protocols for appropriate treatments, including those conditions that warrant immediate attention. The orbital compartment contains a variety of tissues arranged in a fashion reminiscent of Pandora’s box. These tissues can be independently involved in a plethora of disorders which can impose a number of sight-threatening risks. Many prior studies of these matters have laid a foundation for understanding the approximate incidence of various orbital pathologies.