This chapter provides an overview of phyllodes tumors (PT) in the breast, highlighting their histological characteristics, classifications, epidemiology, risk factors, diagnosis, and treatment options. Phyllodes tumors are fibroepithelial neoplasms classified as benign, borderline, or malignant based on histological features and are characterized by rapid growth. They account for a small percentage of primary breast tumors (0.3–1%). Risk factors include age, sex, ethnicity, and genetic mutations. Diagnostic imaging modalities such as ultrasound, mammography, and MRI, as well as pathology, guide treatment. Surgery is the mainstay of treatment; options include partial mastectomy and mastectomy, with considerations for tumor size, location, patient preferences, and aggressiveness of the tumor. Operative anatomy plays a crucial role in ensuring successful surgical outcome, and careful preoperative planning is necessary to minimize complications. Adjuvant treatment, and at times neoadjuvant treatment, is based on the final pathology and multidisciplinary tumor board consensus. Follow-up and surveillance are essential to monitor for recurrence.

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Phyllodes Tumor

  • Alexandra Hernandez,
  • Kelley Benck,
  • Neha Goel

摘要

This chapter provides an overview of phyllodes tumors (PT) in the breast, highlighting their histological characteristics, classifications, epidemiology, risk factors, diagnosis, and treatment options. Phyllodes tumors are fibroepithelial neoplasms classified as benign, borderline, or malignant based on histological features and are characterized by rapid growth. They account for a small percentage of primary breast tumors (0.3–1%). Risk factors include age, sex, ethnicity, and genetic mutations. Diagnostic imaging modalities such as ultrasound, mammography, and MRI, as well as pathology, guide treatment. Surgery is the mainstay of treatment; options include partial mastectomy and mastectomy, with considerations for tumor size, location, patient preferences, and aggressiveness of the tumor. Operative anatomy plays a crucial role in ensuring successful surgical outcome, and careful preoperative planning is necessary to minimize complications. Adjuvant treatment, and at times neoadjuvant treatment, is based on the final pathology and multidisciplinary tumor board consensus. Follow-up and surveillance are essential to monitor for recurrence.