This chapter provides a brief introduction to natural language processing (NLP), an area within artificial intelligence and computational linguistics focused on how computers work with human language. The chapter discusses widely used Python tools for NLP, such as NLTK and spaCy. Furthermore, it explores the applications of NLP in biomedicine, particularly in drug discovery, patient care, and biomedical research. The chapter also briefly describes the role of NLP in interpreting clinical texts and extracting biomedical entities. The overall goal is to provide readers a starting point of understanding NLP and its growing influence on the biomedical field.