Postgraduation NCLEX preparation requires a systematic approach to ensure first-attempt success. This chapter provides that approach, from selecting appropriate study resources to determining test-day readiness. Understanding how to analyze practice test performance and address specific types of errors—knowledge gaps, analysis errors, reading errors, and focus errors—supports effective preparation. Case studies contrast successful and unsuccessful preparation approaches and an interactive learning activity helps students apply their own readiness to a postgraduation prep plan. A comprehensive self-assessment checklist helps graduates evaluate their readiness across multiple domains: administrative preparation, knowledge base, test-taking strategies, and practice test performance. Practical strategies guide graduates through each preparation phase, from maintaining focus during practice tests to managing test-day anxiety. Understanding how and why systematic preparation improves success rates helps graduates implement evidence-based strategies for NCLEX success.