This chapter examines medical dissertations from the long eighteenth century that discuss hope’s positive effects on healing. Early modern medical writings posited that emotions could cause illnesses, urging physicians to study the interplay between emotions and bodily changes. Hope emerged as a crucial healing factor in situations beyond the individual’s control. The chapter explores how writers like Jerome Gaub and William Corp investigated the effects of hope on various conditions, suggesting that hope was the most salutary of emotions, providing bodily strength. The chapter also addresses the treatment of nostalgia, demonstrating that restoring hope was deemed an effective remedy. Finally, it analyses hope’s relationship with related emotions like trust and patience, illustrating hope’s importance in early modern medical contexts.