The work summarizes the conditions of economic relations between individual subjects of economic activity regarding the logistical support of production activities of enterprises in transport hubs. Reasonable expediency of using the methodology of comprehensive assessment of service users of logistics services to improve the technical and operational indicators of production systems. Under the conditions of application of the principles of unification of transport and logistics processes, the technology of servicing cargo flows in production formations is simulated and the method of calculating the efficiency indicators of integrated enterprises is proposed. Based on the calculations, a set of measures is proposed to improve the structure of service provision in integrated transport systems. The practical implementation of the obtained results contributes to increasing the level of reliability of the existing infrastructure of production enterprises of international orientation.