Feedback control synthesis for large-scale particle systems is reviewed in the framework of model predictive control (MPC). The high-dimensional character of collective dynamics hampers the performance of traditional MPC algorithms based on fast online dynamic optimization at every time-step. Two alternatives to MPC are proposed. First, the use of supervised learning techniques for the offline approximation of optimal feedback laws is discussed. Then, a procedure based on a sequential linearization of the dynamics based on macroscopic quantities of the particle ensemble is reviewed. Both approaches circumvent the online solution of optimal control problems enabling fast, real-time, feedback synthesis for large-scale particle systems. Numerical experiments assess the performance of the proposed algorithms.