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Olefin formation from aldehydes and phosphonates. Workup is more advantageous than the corresponding Wittig reaction because the phosphate by-product can be washed away with water. Typically gives the E- rather than the Z-olefins.

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Horner–Wadsworth–Emmons Reaction

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Olefin formation from aldehydes and phosphonates. Workup is more advantageous than the corresponding Wittig reaction because the phosphate by-product can be washed away with water. Typically gives the E- rather than the Z-olefins.