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Doebner reaction, also known as Doebner quinoline synthesis and Doebner hydrogen-transfer reaction. It is a three-component coupling reaction of an aniline, pyruvic acid, and an aldehyde to provide a quinoline-4-carboxylic acid. Cf. Povarov reaction.

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Doebner Reaction

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Doebner reaction, also known as Doebner quinoline synthesis and Doebner hydrogen-transfer reaction. It is a three-component coupling reaction of an aniline, pyruvic acid, and an aldehyde to provide a quinoline-4-carboxylic acid. Cf. Povarov reaction.