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Thermal or acid-catalyzed condensation of anilines with β-ketoesters leads to quinolin-4-ones. Cf. Combes quinoline synthesis.

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Conrad–Limpach Reaction

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Thermal or acid-catalyzed condensation of anilines with β-ketoesters leads to quinolin-4-ones. Cf. Combes quinoline synthesis.