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Three-component condensation (3CC), one of the multicomponent reactions (MCRs), of carboxylic acids, C-isocyanides, and carbonyl compounds to afford α-acyloxycarboxamides. Also known as three-component reaction (3CR). Cf. Ugi reaction.

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Passerini Reaction

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  • 发表日期：

    2026年

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  • Jie Jack Li

摘要

Three-component condensation (3CC), one of the multicomponent reactions (MCRs), of carboxylic acids, C-isocyanides, and carbonyl compounds to afford α-acyloxycarboxamides. Also known as three-component reaction (3CR). Cf. Ugi reaction.