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FLASH radiotherapy (RT) is a new form of RT delivering the dose in milliseconds instead of minutes for conventional RT. This FLASH RT appears much less toxic on normal tissues while the effect on tumors is maintained intact or even improved for hypoxic tumors, as compared to conventional RT. This overview is summarizing the state of the art of FLASH RT and emphasizes the most important features of FLASH that could be exploited for clinical translation.

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Innovation in Radiotherapy: FLASH Therapy

  • 章节

  • 出版模式：

    开放获取

  • 发表日期：

    2025年

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  • Jean Bourhis,
  • Edouard Romano,
  • Olivier Gaide,
  • Veljko Grilj,
  • Jean-Francois Germond,
  • Till Boelhen,
  • Raphael Moeckli,
  • Remy Kinj

摘要

FLASH radiotherapy (RT) is a new form of RT delivering the dose in milliseconds instead of minutes for conventional RT. This FLASH RT appears much less toxic on normal tissues while the effect on tumors is maintained intact or even improved for hypoxic tumors, as compared to conventional RT. This overview is summarizing the state of the art of FLASH RT and emphasizes the most important features of FLASH that could be exploited for clinical translation.