According to FAO data, aflatoxins contaminate a quarter of the world’s crops annually. The temperature at which most aflatoxins are produced is 33 °C. Due to the movement of agricultural products around the world, no region is free of aflatoxin. Aflatoxins B1, B2, G1, and G2 can be collected in dust in food processing plants (cocoa, coffee, and spices). The risk of hepatocellular carcinoma (HCC) is significantly increased for subjects with high urinary concentrations of aflatoxin metabolites. Their urinary metabolites are aflatoxin-N7-guanine adducts in urine.

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Human Exposure to Aflatoxins

  • Vladan Radosavljevic

摘要

According to FAO data, aflatoxins contaminate a quarter of the world’s crops annually. The temperature at which most aflatoxins are produced is 33 °C. Due to the movement of agricultural products around the world, no region is free of aflatoxin. Aflatoxins B1, B2, G1, and G2 can be collected in dust in food processing plants (cocoa, coffee, and spices). The risk of hepatocellular carcinoma (HCC) is significantly increased for subjects with high urinary concentrations of aflatoxin metabolites. Their urinary metabolites are aflatoxin-N7-guanine adducts in urine.