Strictly speaking, Global Bioethics was born in 1971, with Van Rensselaer Potter (1911–2001), the oncologist who gave birth to the term bioethics. His original intuition was related to the global issues of the future, interdisciplinary dialogue and the survival and quality of life of the human species. Since the nineties of the previous century, the growing globalization of political, environmental, social, and cultural discussions has led to the characterization of what has been recovered as Global Bioethics. This Chapter is dedicated to that discussion. It closes with a presentation of Hans Küng, who insists on a “global ethical frame of mind”, arising from an awareness of what we have done to our environment and our humanity.