Vision-based systems provide non-contact sensory input for processing and feedback, expanding the capabilities of industrial automation applications. Prediction using ANNs aids such conformities in navigating nonlinear computational landscapes. They map the plethora of potential outcomes or zones of uncertainty introduced by the system’s constituents onto a set of feasible options for action. A measure of intelligence is transferred to robotic systems through the use of trained networks. Two uses of machine vision are presented here. The 3 DOF robotic assembly enables precision cutting of fragile materials with the help of visual guiding and pixel elimination. The 6-degrees-of-freedom robot uses a combination of visual feedback from an onboard camera and supervision from an external camera to achieve its goals. Pick-and-place operations are executed with a switching control method. Both systems improved in terms of computing time and convergence once ANN was used to make the strategies intelligent. The retrieved scene image features are put to use by the networks in a variety of ways. The simulation and experimental results that back up the suggested approaches demonstrates the value of artificial neural network in machine vision applications.