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The brain is the core of the body’s nervous system and the locus of various functions like cognition, personality, mood, speech, language, senses, motor responses, and functional coordination with peripheral organs therefore, it needs excellent functional capability, which reflects in our various responses to different conditions. Essential nutrients like polyunsaturated omega-3 fatty acids offer great benefits to brain health in addition to various favorable effects on other cell types. These omega-3 fatty acids reduce cholesterol and triglycerides, which have implications for age-related neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Hence, these could be considered in the advancement of therapeutics for neurodegenerative conditions. In this chapter, we are giving insights regarding the probable therapeutic significance of omega-3 fatty acids in age-related CNS neurodegenerative diseases as well as its brief role in overall human health.

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Therapeutic Implications of Omega-3 Fatty Acids in CNS-Neurodegenerative Diseases: Reappraise the Pre-Clinical and Clinical Findings

  • 章节

  • 发表日期：

    2025年

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  • Ashish Singh,
  • Pratibha Tripathi,
  • Rashmi Saini,
  • Sarika Singh

摘要

The brain is the core of the body’s nervous system and the locus of various functions like cognition, personality, mood, speech, language, senses, motor responses, and functional coordination with peripheral organs therefore, it needs excellent functional capability, which reflects in our various responses to different conditions. Essential nutrients like polyunsaturated omega-3 fatty acids offer great benefits to brain health in addition to various favorable effects on other cell types. These omega-3 fatty acids reduce cholesterol and triglycerides, which have implications for age-related neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis. Hence, these could be considered in the advancement of therapeutics for neurodegenerative conditions. In this chapter, we are giving insights regarding the probable therapeutic significance of omega-3 fatty acids in age-related CNS neurodegenerative diseases as well as its brief role in overall human health.