The aviation sector faces big challenges in order to promote its sustainable growth, and in recent years, this sector has been pioneering leading strategies to achieve its decarbonization. Among them, the production and use of sustainable aviation fuel highlights. This biofuel can be used in existing aircraft, guaranteeing technical, safety, and environmental criteria. Nevertheless, the main challenge is the achievement of economic feasibility, with regard to its fossil counterpart. In this context, the biorefinery is a processing scheme that allows the complete use of biomasses for the production of biofuels, value-added products as well as bioenergy. In this processing scheme, the profitability relies on several products, which can help to reach the economic feasibility of this aviation biofuel. Therefore, this chapter presents a revision on the use of biorefineries for the production of sustainable aviation fuel. Moreover, future trends related to the production of this biofuel through biorefineries are discussed.