Acute diverticulitis is an inflammatory condition of the colon’s diverticular pouches. While physical therapy is not a primary treatment, it can play a supportive role in managing associated symptoms. This chapter explores the potential benefits of physical therapy in alleviating pain, promoting mobility, and enhancing overall well-being for individuals with acute diverticulitis, facilitating the recovery of this acute condition. By incorporating targeted exercises, manual therapy, and lifestyle modifications, physical therapy may contribute to a comprehensive approach in conjunction with conventional medical treatments, enhancing the overall quality of life for affected individuals.