In this digital era the increased manufacturing and consumption of electronics is causing major concern to environmentalists because of the nature and composition of the electronics that are discarded, i.e., e-wastes. The e-wastes are a serious cause for polluting soil mainly with metal toxicity. Discarded keyboards, mouse, RAM, mobile phones, refrigerators, televisions, and printed circuit boards (PCBs) are all in the category of e-wastes. These wastes are main reason for contamination of natural resources with metals like Cu, Ag, Ni, Mo, Au, Zn, Pb, Co, Cr, Sn, Fe, and Pd. But it has been researched that these metals can be removed using microbes, the technique of bioleaching. In the process of bioleaching, metals are extracted from ores and other materials containing metals. Major classes of bacteria involved in bioleaching are chemolithotrophic acidophiles (Acidithiobacillus ferroxidants, Acidithiobacillus thiooxdants, and Leptospirillum ferrooxidants and heterotrophs like Sulfolobus. Many factors are determinants of the bioleaching process; such as temperature, pH, aeration, microbe used, substrate used for growth of microbes and nutrients available to microorganism. ICP-MS is mainly used for determining the quantitative metal content in the e-waste samples being used for metal recovery.