This case study examines the design and implementation of a CLIL (Content and Language Integrated Learning) college English course aimed at fostering global citizenship and competence at Korean Bible University in Seoul, South Korea. Developed in 2020 using the backward design approach, the course focused on four key domains: globalization and global citizenship, global competence, technology tools, and English communication. Delivered online over two semesters in 2021 during the pandemic, the course integrated UNESCO value-based learning resources and the PISA global competence framework. Activities included multimedia analysis, personal reflections, and English presentations, supported by translanguaging and machine translation (MT) to enhance both language acquisition and understanding of global issues. Findings revealed the course’s effectiveness in boosting students’ global awareness, self-efficacy, language proficiency, and engagement with global citizenship concepts. The transformative experience for students and teachers highlights the potential of combining value-driven content, MT-supported translanguaging, and collaborative learning in CLIL contexts.