Complete mole, also known as the “classic” hydatidiform mole, is the prototype of molar gestation bearing the traditional description of “hydatid,” e.g., grape-like structures at the time of evacuation, a term that was coined by Smellie in 1752. The historical tale of “365 babies” of the Dutch Countess Margaret of Henneberg likely depicts a case of a well-developed complete mole. Well-developed complete moles evacuated during the second trimester are highly characteristic both clinically and pathologically so that their diagnosis can be made even without microscopic examination. However, the clinical and pathological presentation of complete moles has drastically changed since the 1970s because of modern reproductive medicine (ultrasensitive serum hCG measurement and early ultrasound monitoring), and most of the complete moles are nowadays evacuated in the early first trimester without fully developed clinical and pathological characteristics, and in fact, many patients presented with missed abortions without even a suspicion of molar gestation.