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This is a patient with anaplastic thyroid cancer who had received two cycles of lenvatinib and pembrolizumab and subsequently developed acute pneumatosis intestinalis and immune-mediated colitis. He was treated with antibiotics, oxygen, and bowel rest with symptomatic remission and resolution on repeat imaging after 7 days. The patient unfortunately expired from cardiac arrest 3 weeks after hospital discharge.

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Pneumatosis Intestinalis Following Immune Checkpoint Inhibitor Therapy

  • 章节

  • 发表日期：

    2025年

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  • Gabriel Sperling,
  • Yang Lu,
  • Malek Shatila,
  • Krishnavathana Varatharajalu,
  • Bryan Schneider,
  • Anam Khan,
  • Yinghong Wang

摘要

This is a patient with anaplastic thyroid cancer who had received two cycles of lenvatinib and pembrolizumab and subsequently developed acute pneumatosis intestinalis and immune-mediated colitis. He was treated with antibiotics, oxygen, and bowel rest with symptomatic remission and resolution on repeat imaging after 7 days. The patient unfortunately expired from cardiac arrest 3 weeks after hospital discharge.