This chapter discusses climate neutrality in the context of sustainable production and sustainable consumption as crucial approaches to combating global warming and achieving ecological harmony. Using the Systematic Literature Review (SLR) approach and proceeding from the Population, Intervention, Context, and Outcome (PICO) framework, the study integrates global views and regional findings to identify potential barriers, enablers, and trends toward sustainability. The study sample consisted of thirty-nine seminal studies. Specific recommendations state the shortcomings that have been holding the development back, including the financial and technological factors affecting the sustainability of production, cultural and cost considerations regarding consumption, and the disparities between the global and regional trends toward climate goals. Technological and policy change and governance approaches are suggested to be the four critical game-change levers for progress toward climate neutrality. Moreover, cases always highlight excellence from global adversaries and successes derived from mass actions that are cardinal to South Asia’s advancement. The implications for the chapter are policy practitioners, organisations, and civil society by offering the roadmap that should guide stakeholder sustainability integration, advance the capabilities of new technologies, and build global collaboration. This research feeds into the existing literature on climate change by offering a rational and research-backed solution to the problem of climate change.