The constant evolution of the fashion and textile sector is characterised by high specialisation and hyperconnectivity. This scenario forces the industry to adapt quickly, facing significant challenges to remain competitive. These challenges include the need for constant innovation, and therefore, the concept of digitalisation emerges to revolutionise the textile and fashion industry, giving rise to a new way of designing, producing, and consuming fashion. Amidst this digital transformation, Design is fundamental in adapting to new technological and sustainable demands. Thereby, this article, within the scope of Design, more specifically Fashion Design has the main objective of promoting the growth and dissemination of digitalisation in the fashion and textile industry. Focusing on the impact that design can have on this process, the aim is to improve professional skills in the field of digital manufacturing, through co-design between designers and companies, promoting more sustainable and conscious design practices. Therefore, through a comprehensive literature review, a qualitative methodological approach was adopted, which included observational methods during visits to companies and at events with stakeholders. The results, as well as the discussion generated, explore the challenges and opportunities of digital transformation in fashion manufacturing, offering both a current and future vision for the sector.