This chapter examines the theme of meaning and shows how meaning is not what we impose on nature, but what we respond to in our various made artifacts. This is to say that nature is intelligible to us and that central to this intelligibility is our relation to making. Making discloses materiality as both mouldable and recalcitrant, with its own temporality in tension with the action of the maker. This relation of acceptance and recalcitrance in materiality is evident in the process of ruination, which shows matter in its agency and shows building to be itself an event of material history. Drawing on the threefold structure of the self as body, soul and spirit, articulated in part one, this chapter shows that any unmediated opposition between natural and artificial, intelligible and unintelligible, rests on a prior problematic dualism of body and mind. Idea formation and making are not opposed to the natural but rather occur in and through the natural.