Antibody-drug conjugates (ADCs) have come to the age of fruition following a long period of trials and errors. Eleven ADCs have been approved by the Food and Drug Administration (FDA) thus far and many more are in the development pipelines. This chapter provides the current landscape of ADC drug discovery and development. It summarizes the major players in ADC drug development worldwide, recently completed or currently running late-stage clinical trials registered in the United States, recently US patents issued, and patent applications published. In addition, the cost and outcomes aspects of ADC drug therapy are discussed.

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Major ADC Companies, Current Late-Stage Clinical Trials, Recent Patents Issued and Patent Applications Published, and Cost Analysis of Drug Therapy

  • Jeffrey Wang,
  • Aryana Sepassi,
  • Jonathan H. Watanabe

摘要

Antibody-drug conjugates (ADCs) have come to the age of fruition following a long period of trials and errors. Eleven ADCs have been approved by the Food and Drug Administration (FDA) thus far and many more are in the development pipelines. This chapter provides the current landscape of ADC drug discovery and development. It summarizes the major players in ADC drug development worldwide, recently completed or currently running late-stage clinical trials registered in the United States, recently US patents issued, and patent applications published. In addition, the cost and outcomes aspects of ADC drug therapy are discussed.