Artificial Intelligence if one end has empowered it to provide better healthcare, it has also created a widespread concern related to security and privacy like Phishing, Malware, Ransomware, Data Theft and Hacking of Iot Devices. This chapter aims to provide a complete view of various security concerns that arise in AI enabled healthcare systems by initially providing insights into explaining types of attack and mechanisms for cyber attacks with examples. Later in chapter Role of AI in healthcare security is explained in details by providing sufficient details about challenges and Risks in adoption of AI for healthcare. T he chapter further has necessary explanation about the best practices adopted in industry while adopting AI in healthcare whereby the concepts like backward integration, governance and Trust Frameworks.