Robotics and automated systems are transforming tropical disease management by improving surveillance, diagnostics, treatment, and logistics. This chapter explores how automation and robotics enhance the effectiveness of public health initiatives in tropical disease control, with applications ranging from automated laboratories and drone technology to robotic patient care and disinfection systems. Automated systems, such as high-throughput screening and laboratory automation, increase testing efficiency, reduce human error, and enable cost-effective operations, significantly improving research and response times in managing tropical diseases. Drone technology has revolutionized disease surveillance and vector control, offering remote area access and rapid data collection, essential for monitoring outbreaks and ensuring rapid interventions. Robotics in patient care improves healthcare delivery by reducing infection risks, supporting healthcare professionals, and automating routine tasks in resource-limited settings. Automated sanitation and disinfection technologies are critical in enhancing disease control by addressing environmental transmission factors. This chapter also examines the broader implications of sustainable development in integrating these technologies into tropical disease management, emphasizing efficiency, scalability, resource optimization, and long-term sustainability. The adoption of robotics and automation offers substantial potential for improving the quality and reach of healthcare in tropical disease-endemic regions, contributing to more effective and sustainable public health strategies.