Head and neck cancers (HNCs) account for approximately 10% of all cancers with about 90% of them being squamous cell carcinoma. Surgery represents the mainstay of treatment for small, well-localized, and low-grade salivary gland carcinomas. In a clinical trial of BNCT, it was especially effective for patients with recurrent salivary gland carcinomas; the 3-year overall survival rate was about 60% or more. A clinical trial using accelerators in Japan on 13 recurrent and locally advanced non-SCC patients showed an overall response rate of 69.2%; the disease control rate was 100%, with a 1-y/2-y overall survival rate of 100/100%, respectively.

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Clinical Results: Salivary Gland Cancer

  • Teruhito Aihara,
  • Junichi Hiratsuka

摘要

Head and neck cancers (HNCs) account for approximately 10% of all cancers with about 90% of them being squamous cell carcinoma. Surgery represents the mainstay of treatment for small, well-localized, and low-grade salivary gland carcinomas. In a clinical trial of BNCT, it was especially effective for patients with recurrent salivary gland carcinomas; the 3-year overall survival rate was about 60% or more. A clinical trial using accelerators in Japan on 13 recurrent and locally advanced non-SCC patients showed an overall response rate of 69.2%; the disease control rate was 100%, with a 1-y/2-y overall survival rate of 100/100%, respectively.