There has been little focus on bereavement following addiction-related deaths, though research on bereaved persons following substance-related deaths, and drug-related death (DRD) in particular, has been given more attention in recent years. This chapter sheds light on the experiences of those left behind after losing someone to addictive behaviors such as high-risk drug use. DRD has emerged as a pressing global public health concern. The prevalence of DRDs, especially involving synthetic opioids, has escalated in many countries. Such deaths not only tragically cut short lives but also cast a long shadow of sorrow upon those connected to the deceased. In this chapter, we focus on grief among family members and friends. Bereaved individuals seldom grieve in isolation. Instead, they navigate this challenging emotional landscape alongside family members and their broader social networks. Two comprehensive research projects are described. Providing background in a pioneering study, the first of these, conducted in the United Kingdom, explores the experiences of bereaved individuals following substance-related deaths (i.e., alcohol- and DRDs). The chapter then focuses primarily on the second research project, reviewing our own research, which is based in Norway and has a narrower focus exclusively on DRD bereavement. By exploring the complex landscape of addiction-related bereavement, this chapter hopefully contributes to a more comprehensive understanding of its related phenomena. It emphasizes the importance of recognizing grief as a multifaceted social experience, one which necessarily becomes integrated into the dynamics of family and friendship circles within a cultural context. We advocate an acknowledgment of the life situation of people who are bereaved by addiction-related deaths and for broad-spectrum, tailored help and support systems to aid those coping with the aftermath of addiction-related deaths.