This chapter introduces the foundational concepts and diverse approaches to clinical supervision in Latin America, providing a comparative overview of eight countries in the region. It highlights the historical, cultural, and socio-political contexts shaping supervision practices, while examining their commonalities and distinct characteristics. Despite significant progress in psychotherapy training and supervision, challenges such as insufficient regulation, lack of formalized training programs for supervisors, and barriers to equitable access persist across the region. The chapter emphasizes the influence of cultural diversity and socio-economic disparities on supervision practices, particularly in addressing the needs of marginalized communities. Notable differences in supervision preparation, ranging from self-learning and tutorial development to formalized training programs, are explored alongside country-specific examples. The chapter also reflects on the integration of multicultural competencies, drawn from U.S. models, to inform supervision practices in the region. With increasing efforts toward systematic training and regulation, this chapter underscores the need for culturally sensitive and evidence-based approaches to clinical supervision, advocating for ongoing collaboration and the exchange of best practices across Latin America.