This chapter offers a glimpse into the mental worlds of a uniquely Indigenous—and increasingly militant—eighteenth-century Gulf South. Building upon the historiography of fear, rumor, and information networks in early America, the chapter explores Indigenous apprehensions about epidemics, slaving, and extermination. As Max Flomen argues, “gossip” and “bad talk” about colonial efforts to enslave, exterminate, or dispossess their people were central to the Natchez, Meskwaki (Fox), and Choctaw wars of the era—and would continue to drive Native militancy and uprisings during the era of the Seven Years’ War. Notably, Flomen finds extensive cooperation between Native and African peoples and points to the role of plantation slavery in congealing Native fears of expropriation and deportation. From Flomen’s study of the wider Louisiana region, it becomes clear that an evolving ideology of anti-colonial resistance circulated far and wide during the eighteenth century, as diverse Indigenous and African rebels often engaged in mutually intelligible “bad talk.”