Chapter “Advancing the Field of Entrepreneurial Education: Leveraging a Design Science Approach for Educating the Change Agents of the Future” sets the stage for why a design science research (DSR) methodology could significantly benefit the development of entrepreneurial education for both researchers and practitioners. The chapter argues that DSR can demystify the “black box” of entrepreneurial education and address the current epistemological challenges within the field. By exploring the literature on educational effectiveness, the chapter advocates for a shift towards an ecological approach, aligning well with DSR principles. This approach emphasizes the development of “evidence strategies” over rigid best practices, advocating for adaptable methods that educators can implement across varied contexts. Concluding with a call to action, the book aims to promote DSR among entrepreneurial education researchers and educators, empowering them to become architects of entrepreneurial learning equipping students to become the next generation of change agents prepared to address pressing societal challenges.