The chapter focuses on investigating the photodissociation of hemoglobin complexes under external optical radiation. Methods for non-invasive determination of the relative concentration (saturation) of oxy- and carboxyhemoglobin in arterial blood flows are examined. The experimental study explores the dependency of laser-stimulated photodissociation of hemoglobin on the wavelength of external irradiation, the temperature of surrounding biotissue, and the distance between the areas of irradiation and measurement, allowing for an assessment of recombination processes. The findings reveal that the photodissociation process reaches saturation at approximately 11·1016 photons per second. The outcomes of this research can find application in low-intensity laser therapy for planning and conducting therapeutic procedures.

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Photodissociation of Hemoglobin Molecules in Vivo Under External Irradiation

  • Serhii Mamilov,
  • Mykhailo Bezuglyi

摘要

The chapter focuses on investigating the photodissociation of hemoglobin complexes under external optical radiation. Methods for non-invasive determination of the relative concentration (saturation) of oxy- and carboxyhemoglobin in arterial blood flows are examined. The experimental study explores the dependency of laser-stimulated photodissociation of hemoglobin on the wavelength of external irradiation, the temperature of surrounding biotissue, and the distance between the areas of irradiation and measurement, allowing for an assessment of recombination processes. The findings reveal that the photodissociation process reaches saturation at approximately 11·1016 photons per second. The outcomes of this research can find application in low-intensity laser therapy for planning and conducting therapeutic procedures.