Despite the multiple ways of being and knowing, the design field has historically adopted a universal approach in which one size (or design) fits all. In this book chapter, I challenge this assumption in the computational and interaction design domains, arguing in favor of embracing plurality inherent in all human experiences. I introduce [un]making with____ as a design approach that achieves inclusive interactions. I define “unmaking” here as a conscious method of deconstructing and iteratively remaking understandings, processes, and tools; in a sense, unmaking reveals new insights that make space for new ideas to emerge. The concept of [un]making with____ emphasizes co-designing with people, rather than for them, and acknowledges that we design with tools, machines, and individual circumstances, allowing for multiple worldviews. Building on this, I focus on two levels of investigation: human sensory perception and context. I present three projects from my lab that exemplify the approach. Drawing from these three projects, I discuss how this approach emphasizes design as a web of relations and fosters mutual meaning-making.