The chapter deals with researches related to the applicability obtained results in bioengineering. The firs subchapter related manufacturing plasmon metal nanostructures formation in piezocomposite material controllable in micrometric level for detection and sensing cell-biological particles. In the second subchapter development of active PZT composite microfluidic channel for bioparticle manipulatiāon is presented. The methodology for identification of liquid concentration in the periodic microstructures applying numerical-experimental laser interferometric methods is presented in the third subchapter.