This chapter highlights procedures that are specific to the assessment of a patient with a uveal tumor. These include slit-lamp examination, gonioscopy, binocular indirect ophthalmoscopy, transillumination, and color photography. Preparation of drawings complements imaging and may be useful for documenting disease and planning treatment. Other investigations, such as autofluorescence imaging, optical coherence tomography, and ultrasonography are described in other chapters. It is assumed that a full ophthalmic and systemic history is routinely obtained in all patients in addition to clinically relevant ancillary investigations.